Ligand-Exchange Chromatography of Racemates XI. Complete Resolution of Some Chelating Racemic Compounds and Nature of Sorption Enantioselectivity

Abstract
Results of a systematic study are summarized on chromatographic resolutions of racemic amino acids using ligand exchange on Cu (II) ion-charged poly-styrene type resins containing residues of optically active proline, hydroxyproline, allo-hydroxyproline and azetidine carboxylic acid. Possible variants of the enantioselective complex formation in the resin phase are discussed. Examples of quantitative resolutions of racemic amino acids and members of other classes of chelating organic compounds are given.