Abstract
Nitrate introduced into the rumen of the sheep is reduced to ammonia. Nitrite is an intermediate in this reaction and may accumulate under certain conditions and lead to a partial conversion of blood Hb to methemoglobin. NaNO3 (25 g.) or NaNO2 (10 g.) placed in the rumen, or 2 g. NaNO2 injected intraven., resulted in a methemoglobinemia corresponding to 60% conversion of the total Hb.

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