The Effects of Body Weight on Serum Cholesterol, Serum Triglycerides, Serum Urate and Systolic Blood Pressure*

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Abstract
The effects of body weight and age on serum cholesterol, serum triglycerides, serum urate and systolic blood pressure were examined in 600 male and 400 female blood donors aged 20-49 yr. In the men significant correlations with body mass index were found for 4 variables in each decade. In the women < 40 yr old only the correlation with blood pressure was significant. In the 5th decade the correlations resembled those in the men except for triglycerides. After adjusting for weight, age had no independent influence on the prevalence of hypertriglyceridemia or hypertension in either sex. In men the effect of body weight on the prevalence of hypercholesterolemia was age dependent. Age influenced hyperuricemia independently of weight. In women only serum cholesterol was affected by age after allowing for weight. There was marked clustering of high values of the 4 variables in the heavier men and women and this increased with age. The leanest men and women were free of high values.