Acidification of the Gastric Antruin and Inhibition of Gastric Secretion
- 1 April 1965
- journal article
- research article
- Published by Wolters Kluwer Health in Annals of Surgery
- Vol. 161 (4) , 587-591
- https://doi.org/10.1097/00000658-196504000-00016
Abstract
Acidification of the vagally-denervated antrum in our experiments failed to inhibit: histamine-induced fundic secretion, exogenous gastrin-induced fundic secretion, but inhibited: acetylcholine-induced fundic secretion at a rate of 83.5%. These findings suggest that antral acidification acts as a local mechanism to suppress formation or release of gastrin, and not via an inhibitory hormone.Keywords
This publication has 14 references indexed in Scilit:
- A sensitive technique for gastric pouch collection.1963
- Physiologic Scope of the Antral Inhibitory HormoneAnnals of Surgery, 1962
- Effect of acid in pyloric pouch on response of fundic pouch to injected gastrinAmerican Journal of Physiology-Legacy Content, 1962
- An improved cannula for experimental gastric pouches.1962
- A New Preparation of Gastrin: Preliminary CharacterizationNature, 1961
- Inhibitory Effects of Hydrochloric Acid in Antrum and Duodenum on Histamine-Stimulated Gastric Secretion in Pavlov and Heidenhain Pouch DogsActa Physiologica Scandinavica, 1960
- Techniques in Heidenhain pouch experimentsJournal of Applied Physiology, 1959
- Question of an Inhibitory Hormone From the Gastric AntrumAmerican Journal of Physiology-Legacy Content, 1957
- A study of the gastric antrum as an inhibitor of gastric juice production.1957
- The physiology of the gastric antrum; experimental studies on isolated antrum pouches in dogs.1954