Pyrrole Chemistry. Part XXIX A Re-Examination of the Decarboxylation of 4-Acetyl-, 4-Formyl- and 4-Cyanopyrrole-2-Carboxylic Acids
- 1 March 1987
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 17 (4) , 401-407
- https://doi.org/10.1080/00397918708063917
Abstract
Decarboxylation of the readily available 4-acyl-2-pyrrolecarboxylic acids has been neglected owing to the poor yields reported in the literature. This study shows that high yields are possible under the correct reaction conditions.Keywords
This publication has 15 references indexed in Scilit:
- The Synthesis of 3-Substituted Pyrroles from PyrroleSynthesis, 1985
- A synthesis of 3-substituted pyrroles through the halogen-metal exchange reaction of 3-bromo-1-(triisopropylsilyl)pyrroleThe Journal of Organic Chemistry, 1984
- β-substituted pyrroles via electrophilic substitution of n-triisopropylsilylpyrrole.Tetrahedron Letters, 1983
- Synthesis of 3,4-Bis[trifluoromethyl]-1H-pyrroleSynthesis, 1982
- Pyrrole chemistry XXV: A simplified synthesis of some 3-substituted pyrrolesTetrahedron Letters, 1981
- A simple and efficient route to β-substituted pyrrolesTetrahedron Letters, 1981
- Pyrrole chemistry. XXII. A "one-pot" synthesis of some 4-acylpyrrole-2-carboxaldehydes from pyrroleCanadian Journal of Chemistry, 1980
- 2-(Trichloroacetyl)pyrroles as intermediates in the preparation of 2,4-disubstituted pyrrolesThe Journal of Organic Chemistry, 1978
- Pyrrole chemistry—IXTetrahedron, 1969
- Pyrrole chemistry. VI. Syntheses and electrophilic substitution reactions of some 3-substituted pyrrolesCanadian Journal of Chemistry, 1967