Surgical Treatment of Canalicular Stenosis in Patients Receiving Docetaxel Weekly

Abstract
DOCETAXEL (Taxotere; Aventis, Collegeville, Pa) is an effective chemotherapeutic agent against metastatic breast cancer.1-3 In women with metastatic disease, docetaxel is usually administered as a 1-hour intravenous infusion every 21 days. With this standard administration schedule, the dose-limiting adverse effect is myelosuppression.4 Weekly administration of docetaxel has been studied in phase I and II trials and has proven to be a less myelosuppressive regimen.5,6

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