Surface Markers of Lymphocytes Infiltrating Seminoma Tissue

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Abstract
Infiltrating lymphocytes were separated from human seminoma tissue obtained surgically. The relative distributions of B and T lymphocytes and a subset of T lymphocytes with IgG-Fc receptors [TG cells] were measured by the rosette-forming method in peripheral blood and in seminoma tissue from patients with pure seminoma of the testis. The proportions of T and TG cells were increased in seminoma tissue compared to those of peripheral blood from the same patients; the proportion of B cells did not change. This may correlate with the favorable prognosis of seminoma usually accompanied with lymphocytic infiltration.