Abstract
Patients (61) hospitalized because of asthma and/or allergic rhinitis were given nasal and bronchial challenge tests with diluents containing glycerol. Sixty-two percent of the patients with rhinitis and 37% of those with asthma gave positive reactions. Glycerol should therefore not be used in allergen extracts meant for challenge tests. The non-specific effect of glycerol seems to be cumulative with increasing dose.

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