DISSOCIATION OF HEMOLYTIC AND LYMPHOCYTE-TRANSFORMING ACTIVITIES OF STREPTOLYSIN S PREPARATIONS

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Abstract
The ability of streptolysin S preparations to induce high percentages of transformation in human peripheral blood lymphocytes was confirmed in a series of apparently healthy donors. Transforming activity was not demonstrated in the two media used for streptolysin S production, nor in control preparations in which a strain each of Streptococcus viridans, Staphylococcus aureus (nonhemolytic), and Diplococcus pneumoniae was substituted for the beta hemolytic streptococcal strain used for streptolysin S production.