Autonomic Neuropathy and Inappropriate Secretion of Antidiuretic Hormone Occurrence in a Patient With Bronchogenic Carcinoma

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Abstract
WHILE the syndrome of inappropriate secretion of antidiuretic hormone is a well-recognized complication of bronchogenic carcinoma,1its combination with autonomic dysfunction seems much less common.2,3There appears to be only one previous report describing a patient in whom loss of sweating, hypotension, and nonobstructive urinary retention were noticed.4Another report describes this combination with a pancreatic carcinoma.5 A patient with the combined effects of autonomic neuropathy and hyponatremia had metastatic bronchogenic carcinoma. Report of a Case A 65-year-old man had a one-year history of severe constipation, 6-kg weight loss, impotence, and two episodes of collapse in which he had lost consciousness. Examination, sigmoidoscopy, barium enema examination, and chest roentgenograms were normal, but the serum sodium level was 120 mEq/L. One month later he was admitted as an emergency with attacks of feeling distant in which he could not speak and other episodes in which he lost