Substitutive-Inhibitory Gamma Globulin Therapy as Prevention of Stillbirth in Rh–Incompatibility

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Abstract
A pregnant anti-Rh sensitized woman was treated with massive doses of gamma-globulin. Subsequently there was no increase of the antibody-titer until 1 month after delivery of a Rh-positive healthy boy. These results are parallel to the diminution of anti-sheep red cell agglutinin production in rats (and mice) injected regularly with high quantities of homologous serum. Substitutive-inhibitory gamma-globulin treatment seems to be useful in preventing stillbirth due to mater no-fetal blood incompatibility.