Changes in response to a dopamine receptor antagonist in rats with escalating cocaine intake
- 28 November 2003
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 172 (4) , 450-454
- https://doi.org/10.1007/s00213-003-1682-9
Abstract
Prolonged access to cocaine self-administration (long access or LgA) produces an escalation in drug intake not observed with limited access to the drug (short access or ShA). The present study tested the hypothesis that escalating use of cocaine is associated with chronic alterations in dopamine neurotransmission.Keywords
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