Phase I-II study of ftorafur and methyl-ccnu in advanced colorectal cancer
- 1 September 1979
- Vol. 44 (3) , 869-872
- https://doi.org/10.1002/1097-0142(197909)44:3<869::aid-cncr2820440312>3.0.co;2-f
Abstract
The combination of Ftorafur (NSC-148958) and methyl-CCNU (NSC-95441) was evaluated in 36 patients with advanced colorectal cancer. The principle toxicities encountered were myelosuppression, gastrointestinal, and neurological. There were no complete responses and only 5/34 (14.7%) patients achieved a partial response. Methyl-CCNU and Ftorafur does not appear to be an effective combination in advanced adenocarcinoma of the colon and rectum.This publication has 9 references indexed in Scilit:
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