New fACEs to the Renin-Angiotensin System
Open Access
- 1 April 2005
- journal article
- review article
- Published by American Physiological Society in Physiology
- Vol. 20 (2) , 91-95
- https://doi.org/10.1152/physiol.00003.2005
Abstract
Inhibition of the angiotensin-converting enzyme (ACE) protects against the progression of several cardiovascular diseases. Recent evidence suggests that some of the beneficial effects of ACE inhibitors can be attributed to the activation of a distinct ACE signaling cascade rather than to the changes in angiotensin II and bradykinin levels. Moreover, at least one other ACE homolog (ACE2) plays a significant role in the regulation of heart and kidney function.Keywords
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