Staphylococcal scalded skin syndrome

Abstract
The form and severity of SSSS will vary with the route of delivery of the toxin to the skin, ranging from the localised bullous impetigo to generalised SSSS involving the entire skin surface.2-4 In the latter, patients are susceptible to poor temperature control, extensive fluid losses, and secondary infections. They may also develop sepsis and present with hypotension, neutropenia, and respiratory distress.5 Antibiotic treatment with β-lactamase resistant semisynthetic penicillins such as flucloxacillin is usually effective.3 6 Outbreaks of SSSS involving a large number of babies in neonatal wards are not uncommon and may persist for a long time if carriers of toxin producing S aureus are not rapidly identified and treated.6-9