Clozapine and N-desmethylclozapine are potent 5-HT1C receptor antagonists
- 15 April 1993
- journal article
- research article
- Published by Elsevier in European Journal of Pharmacology: Molecular Pharmacology
- Vol. 245 (2) , 179-182
- https://doi.org/10.1016/0922-4106(93)90126-t
Abstract
No abstract availableKeywords
This publication has 6 references indexed in Scilit:
- Chronic clozapine treatment down-regulates serotonin 5-HT-1c receptors in rat brainProgress in Neuro-Psychopharmacology and Biological Psychiatry, 1992
- Binding of typical and atypical antipsychotics to 5-HT1C and 5-HT2 sites: clozapine potently interacts with 5-HT1C sitesEuropean Journal of Pharmacology, 1990
- Ethanol administration does not alter dopamine D1 and D2 receptor characteristics in rat brainNeuroscience Letters, 1990
- Determination of clozapine and its N-demethylated metabolite in plasma by use of gas chromatography-mass spectrometry with single ion detectionPsychopharmacology, 1988
- Chronic clozapine treatment of rats down-regulates cortical 5-HT2 receptorsEuropean Journal of Pharmacology, 1983
- Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionBiochemical Pharmacology, 1973