The Graft Versus Leukemia Effect after Bone Marrow Transplantation: A Case Study Using Structural Nested Failure Time Models
- 1 March 1999
- journal article
- Published by Oxford University Press (OUP) in Biometrics
- Vol. 55 (1) , 23-28
- https://doi.org/10.1111/j.0006-341x.1999.00023.x
Abstract
Summary. Over the last decade, J. M. Robins has developed a set of tools for assessing, from observational data, the causal effects of a time‐dependent treatment or exposure in the presence of time‐dependent covariates that may be simultaneously confounders and intermediate variables. This report concerns a case study of the application of one these techniques, G‐estimation using structural nested failure time models, to the problem of assessing the effect of graft versus host disease on leukemia relapse after bone marrow transplantation.Keywords
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