THE EFFECT OF THIAMIN HYDROCHLORIDE ON THE MUSCULAR DYSTROPHY OF AVITAMINOSIS-E

Abstract
Studies upon young weanling rats which had developed various stages of muscular dystrophy, due to a vit. E-deficient diet, revealed that there was a definite response to the oral adm. of massive doses of vit. B1 (thiamin hydrochloride). The response of the individual rat to a definite dose varied according to the severity of muscular dystrophy. The total amt. of thiamin hydrochloride necessary to effect a cure ranged from 4-14 I. U. per rat.