Radiation Necrosis of the Scalp: A Complication of Cranial Irradiation and Methotrexate

1 September 1977

journal article
research article
Published by Radiological Society of North America (RSNA) in Radiology

Vol. 124 (3) , 813-814
https://doi.org/10.1148/124.3.813

Abstract

A case of childhood leukemia with a severe skin reaction following a course of medium dose cranial irradiation and intrathecal methotrexate is presented. Necrosis of the scalp of partial to full thickness resulted. Potentiation of the radiation reaction by methotrexate was the probable cause.

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