PHYTOESTROGENS
Top Cited Papers
- 2 June 2004
- journal article
- review article
- Published by Annual Reviews in Annual Review of Plant Biology
- Vol. 55 (1) , 225-261
- https://doi.org/10.1146/annurev.arplant.55.031903.141729
Abstract
▪ Abstract Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals. These compounds, termed phytoestrogens, include certain isoflavonoids, flavonoids, stilbenes, and lignans. The best-studied dietary phytoestrogens are the soy isoflavones and the flaxseed lignans. Their perceived health beneficial properties extend beyond hormone-dependent breast and prostate cancers and osteoporosis to include cognitive function, cardiovascular disease, immunity and inflammation, and reproduction and fertility. In the future, metabolic engineering of plants could generate novel and exquisitely controlled dietary sources with which to better assess the potential health beneficial effects of phytoestrogens.Keywords
This publication has 183 references indexed in Scilit:
- Soy isoflavonoid equol modulates the growth of benign and malignant prostatic epithelial cells in vitroThe Prostate, 2002
- Time-resolved fluoroimmunoassay of plasma and urine O-desmethylangolensinThe Journal of Steroid Biochemistry and Molecular Biology, 2002
- A pilot study of the effects of phytoestrogen supplementation on postmenopausal endometriumJournal of the Society for Gynecologic Investigation, 2002
- Estrogenic Activity of the Phytoestrogens Naringenin, 6-(1,1-Dimethylallyl)naringenin and 8-PrenylnaringeninPlanta Medica, 2002
- Identification of an Endocrine Disrupting Agent from Corn with Mitogenic ActivityBiochemical and Biophysical Research Communications, 2002
- Expression of prostate‐specific antigen is transcriptionally regulated by genistein in prostate cancer cellsMolecular Carcinogenesis, 2002
- Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolaseFEBS Letters, 2000
- Bioavailability of genistein, daidzein, and their glycosides in intestinal epithelial Caco-2 cellsEnvironmental Toxicology and Pharmacology, 1999
- 3'-Prenyl-4'-methoxy-isoflavone-7-O-β-D-(2"-O-p-coumaroly) glucopyranoside, a Novel Phytoestrogen from Sopubia delphinifoliaJournal of Natural Products, 1990
- Enzymatic rearrangement of flavanone to isoflavoneFEBS Letters, 1984