Clinical Relevance of Antibodies to Ro/SS-A and La/SS-B in Subacute Cutaneous Lupus Erythematosus and Related Conditions
- 1 January 1993
- journal article
- review article
- Published by Taylor & Francis in Immunological Investigations
- Vol. 22 (3) , 189-203
- https://doi.org/10.3109/08820139309063402
Abstract
Ro/SS-A autoantibodies are frequently associated with subacute cutaneous lupus erythematosus, neonatal lupus erythematosus and Sjögren's syndrome. The Ro/SS-A autoantigen is a ribonucleoprotein complex consisting of at least four protein components and four small cytoplasmic RNA components designated hY RNA 1, 3, 4 and 5. Three of the Ro/SS-A peptides have been isolated and cloned. The function of this ribonucleoprotein complex is as yet unknown.Keywords
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