eIF4G--A Multipurpose Ribosome Adapter?
- 24 January 1997
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 275 (5299) , 500-501
- https://doi.org/10.1126/science.275.5299.500
Abstract
Messenger RNAs are translated into protein—a complex enterprise. Now, in work from a number of laboratories, one small adapter protein is shown to be a central player in several variations on the process. In his Perspective, Hentze describes how eIF4G serves as an adapter that binds the small ribosome subunit to the messenger RNA, working in different ways when the message has a 7mG cap at its 5 ' end or a polyadenylated tail at its 3 ' end.Keywords
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