A simple method for the isolation of adrenal chromaffin granules on a large scale
- 1 May 1967
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 103 (2) , 480-482
- https://doi.org/10.1042/bj1030480
Abstract
Highly purified chromaffin granules can be obtained from homogenates of either ox, pig, horse or rat adrenal medullae by ultracentrifugation of the large-granule fraction layered on 1.6 M-sucrose solution, by using angle-head rotors. The chromaffin granules are obtained as a pink sediment that is only slightly contaminated by mitochondria and lysosomes.This publication has 11 references indexed in Scilit:
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