Genetics of cell-surface antigens: Regional mapping of three components of the human cell-surface antigen complex, Al, on chromosome 11
- 1 July 1977
- journal article
- Published by Springer Nature in Somatic Cell and Molecular Genetics
- Vol. 3 (4) , 421-429
- https://doi.org/10.1007/bf01542970
Abstract
Cytogenetic analysis has been performed on a series of deletion mutations on human chromosome 11 of AL hybrid clones in which specific markers have been lost as a result of treatment with mutagenic agents. Such analysis has localized the three previously identified components of the AL cell-surface antigen complex to the indicated regions of chromosome 11: a1 and a3:11p13 → 11pter; a2: 11q13 → 11qter. Using these methodologies human lactic dehydrogenase A localization on the short arm as reported by others has been confirmed. Evidence is presented provisionally assigning this gene to 11p13 → 11pter.Keywords
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