Treating Menorrhagia in Primary Care: An Overview of Drug Trials and a Survey of Prescribing Practice
- 1 January 1995
- journal article
- research article
- Published by Cambridge University Press (CUP) in International Journal of Technology Assessment in Health Care
- Vol. 11 (3) , 456-471
- https://doi.org/10.1017/s0266462300008679
Abstract
Menorrhagia can be treated by drug therapy or surgery. General practitioners (GPs) can prescribe drugs to reduce menstrual blood loss as first-line treatment, referring patients for surgical treatment if drug therapy fails. This study examined the efficacy of drugs used to treat menorrhagia and surveyed British GPs to discover the extent to which they prescribed the most effective drugs for this condition. The results suggest that treatment of this condition in primary care falls short of desirable standards. A meta-analysis of randomized trials of drug therapy revealed wide differences in efficacy and side effects. The most effective drug (tranexamic acid) is little used by British GPs, whereas the least effective drug (norethisterone) is the most frequently prescribed.Keywords
This publication has 36 references indexed in Scilit:
- Comparative study of tranexamic acid and norethisterone in the treatment of ovulatory menorrhagiaBJOG: An International Journal of Obstetrics and Gynaecology, 1995
- A comparative study of ethamsylate and mefenamic acid in dysfunctional uterine bleedingBJOG: An International Journal of Obstetrics and Gynaecology, 1991
- A comparison of flurbiprofen, tranexamic acid, and a levonorgestrel-releasing intrauterine contraceptive device in the treatment of idiopathic menorrhagiaAmerican Journal of Obstetrics and Gynecology, 1991
- Role of menstrual blood loss measurements in management of complaints of excessive menstrual bleedingBJOG: An International Journal of Obstetrics and Gynaecology, 1991
- EFFECT OF FENAMATES ON PROSTAGLANDIN E RECEPTOR BINDINGThe Lancet, 1988
- An Objective Evaluation of Flurbiprofen and Tranexamic Acid in the Treatment of Idiopathic MenorrhagiaActa Obstetricia et Gynecologica Scandinavica, 1988
- The effects of danazol mefanamic acid, norethistherone and a progesterone-impragnated coil on endometrial prostaglandin concentrations in women with monorrhagiaProstaglandins, 1987
- Comparative quantitation of menstrual blood loss with a d-norgestrel-releasing IUD and a Nova-T-copper deviceContraception, 1977
- Treatment of Menorrhagia with Tranexamic Acid. A Double-blind TrialBMJ, 1970
- Treatment Of Menorrhagia With An Antifibrinolytic Agent, Tranexamic Acid (Amca): A Double Blind InvestigationActa Obstetricia et Gynecologica Scandinavica, 1967