Abstract
The rationale of the chemical treatment of burns is based on what is known of their pathologic physiology. In the modern therapy of the burned patient the chemical treatment is important, and a thorough understanding of the pathologic physiology is a requisite to the physician who treats the burned patient with intelligence. In this article are presented current concepts of the nature and consequences of a burn wound and the treatment recommended. NATURE OF A BURN WOUND The application of sufficient heat to a body surface to produce a burn sets in motion a sequence of events. The changes which appear in a patient with a burn, mild or severe, within the first hours are manifested as pain, alterations in blood flow, increase in capillary permeability, edema and increased flow in the lymphatic trunks. Necrosis.— In a severe burn the picture is complicated by cell necrosis and its consequences.