ASSOCIATION OF LUPUS ANTICOAGULANT WITH SEVERE VALVULAR HEART-DISEASE IN SYSTEMIC LUPUS-ERYTHEMATOSUS
- 1 April 1988
- journal article
- research article
- Vol. 15 (4) , 597-600
Abstract
Two cases of systemic lupus erythematosus with hemodynamically significant mitral valve dysfunction and associated lupus anticoagulant are reported. Both patients underwent valve replacement and both had thrombus formation on the mitral valve, one pre- and the other postoperatively. Both patients suffered a number of extracardiac thromboses at different times in the course of their illness. The contribution of the lupus anticoagulant to the thrombotic problems, and its possible relationship to the pathogenesis of Libman-Sacks endocarditis are discussed.This publication has 7 references indexed in Scilit:
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