Glaucoma secondary to leukemic infiltration of the iris is a rare condition. Occurrence of leukemic infiltrates into ocular tissues is well known and has been described in detail recently.1-3 This report deals with a patient who developed glaucoma in both eyes as a result of leukemic involvement of the irides; x-ray therapy was successful in treatment of the iris lesions and resolution of the glaucoma. Report of a Case The patient, a 6½-year-old white girl, was first seen on the ophthalmology service at Children's Hospital of Denver on April 10, 1964, with complaints of red watery eyes and poor vision of several weeks' duration. History. —A diagnosis of acute lymphogenous leukemia had been established in August 1962. For 19 months she had been treated with various medications including prednisone, mercaptopurine (Purinethol), vincristine sulfate (Oncovin), cyclophosphamide (Cytoxan), and packed red cell transfusions. Except for a severe relapse in December 1963,