Therapy of Infections with Oral Cephalexin

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Abstract
11 patients with postoperative wound infections and 11 with septicemia caused by penicillinase producing Staphylococcus aureus, 22 patients with lower respiratory tract infections and 6 with erysipelas were treated with 1 g cephalexin orally 4 times daily. The septicemia patients received initial intravenous therapy with 1 g cephalexin, 4–6 times daily for 1–4 days. 44 patients were cured and 3 improved; 2 patients with pneumonia, 1 caused by Staphylococcus aureus and the other by Hemophilus influenzae, and 1 septicemia patient failed to respond to therapy. 8 patients developed minor side-effects. Oral cephalexin is useful in the treatment of lower respiratory tract and soft tissue infections. It is also useful in the treatment of Staphylococcus aureus septicemia which initially has been controlled by parenteral antibiotics.

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