CRETINISM AND MYXEDEMA PRODUCED EXPERIMENTALLY IN SWINE

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Abstract
In swine the thyroid gland is situated on the ventral surface of the trachea in the median line, just anterior to the thoracic aperture in the angle formed by the carotid arteries and jugular veins. It is composed of two lateral lobes fused in the median line to form a single organ. Swine respond quickly to thyroid deficiency with definite symptoms. Distinct parathyroid glands were not found, but islands of parathyroid tissue were demonstrated in accessory thyroid glands. Parathyroid tetany did not develop following complete thyroidectomy. Animals operated on before puberty showed a more marked reaction. Swine from which the thyroid had been removed, apparently were hypersusceptible to disease.

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