Abstract
A satisfactory classification of the large group of congenital and early infantile diseases of the brain, Brissaud'sencéphalopathies infantiles, does not as yet exist, despite a vast accumulation of reports of cases and descriptions published during the past seventy years. A number of more or less well defined syndromes, such as amaurotic idiocy and Schilder's disease, have been delineated, it is true, but there remains a motley assortment of disturbances—traumatic, inflammatory and degenerative. These are generally designated as infantile or congenital encephalitis in such a loose way that "encephalitis" has scarcely any clinical or anatomic significance in the realm of diseases of the new-born. All this bespeaks a lack of understanding of the etiology and pathogenesis, on which some light may be shed by the observations in the case to be reported. REPORT OF CASE History. —A girl, aged 7 weeks, was admitted to the Presbyterian Hospital, to the service

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