Transamidase Reactions Involved in the Enzymic Coagulation of Semen: Isolation of γ-Glutamyl-ε-Lysine Dipeptide from Clotted Secretion Protein of Guinea Pig Seminal Vesicle
- 1 August 1972
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 69 (8) , 2322-2325
- https://doi.org/10.1073/pnas.69.8.2322
Abstract
New supportive evidence is advanced in favor of the hypothesis that the enzymic coagulation of guinea pig semen involves transamidase reactions that result in the formation of γ-glutamyl-ε-lysine intermolecular cross linkages between molecules of a basic protein in seminal vesicle secretion. The dipeptide γ-glutamyl-ε-lysine was isolated in large quantities from proteolytic digests of the coagulated basic vesicular secretion protein that comprises the seminal clot.Keywords
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