Use of mathematical models for understanding the dynamics of gene amplification
- 31 August 1993
- journal article
- review article
- Published by Elsevier in Mutation Research/Environmental Mutagenesis and Related Subjects
- Vol. 292 (1) , 17-24
- https://doi.org/10.1016/0165-1161(93)90004-j
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Amplification of the N-myc gene in human neuroblastomas: tandemly repeated amplicons within homogeneously staining regions on different chromosomes with the retention of single copy gene at the resident siteMutation Research/Reviews in Genetic Toxicology, 1992
- A branching process model of gene amplification following chromosome breakageMutation Research/Reviews in Genetic Toxicology, 1992
- Amplification of the dihydrofolate reductase gene in methotrexate-resistant Chinese hamster cellsMutation Research/Reviews in Genetic Toxicology, 1992
- Regularities of karyotypic evolution during stepwise amplification of genes determining drug resistanceMutation Research/Reviews in Genetic Toxicology, 1992
- Drug resistance as a dynamic process in a model for multistep gene amplification under various levels of selection stringencyCancer Chemotherapy and Pharmacology, 1992
- The dynamics of gene amplification described as a multitype compartmental model and as a branching processMathematical Biosciences, 1991
- Chromosomal destabilization during gene amplification.Molecular and Cellular Biology, 1990
- Double minute chromosomes can be produced from precursors derived from a chromosomal deletion.Molecular and Cellular Biology, 1988
- The Effect of Drug Schedule on Responsiveness to ChemotherapyAnnals of the New York Academy of Sciences, 1987
- Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease StageScience, 1984