Lifelong variations in heart rates in SPF Sprague Dawley rats of both sexes

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Abstract
In unanesthetized Sprague Dawleys, SPF, of both sexes, housed indl 12:12 (110 lux), at a temperature of 18–23°C and a hygrometry of 60–75%, the measurements of heart frequencies during most part of their life point out a continuous decrease with age and an always higher (40–20 c. min−1) heart rate in females than in males. Significant correlations between rate and body weight can account for these heart which corresponds to the growth period, a linear relationship was established between Log heart rate (y;c. min−1) and Log body weight (x; gram); for males: Logy=−0.122 Logx+Log 938 and for females: Logy=−0.166 Logx+Log 1217. After the age of 600 days, which corresponds to senescence, decreases in heart rate as well as in body weight were observed in both sexes.

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