THERAPEUTIC VALUE OF AMMONIACAL SILVER NITRATE IN FUNGOUS INFECTIONS OF THE NAILS
- 1 June 1948
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 57 (6) , 935-941
- https://doi.org/10.1001/archderm.1948.01520190014003
Abstract
FUNGOUS infection of the nails, or onychomycosis, is more frequent than has been suspected in the past. The anatomic structure of the nail, with its high content of keratin, provides a good location for the development of certain of the pathogenic fungi. The thickness of the nail tissue and its comparative impermeability cause infections of the nails to be among the most resistant to treatment of the superficial mycoses. The organism responsible may be Candida albicans or one of the species of dermatophytes, such as Trichophyton rubrum or Epidermophyton floccosum; mixed infections are apparently uncommon in this particular type of disease. The invading fungus penetrates the nail along the free edge and grows toward the matrix, gradually infecting the entire nail and the nail bed and may involve the matrix itself. The nail becomes discolored and turns dirty yellow or brown, losing its luster and presenting a dull uneven surfaceKeywords
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