Incidence of autoantibodies in cancer patients.

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  • 1 October 1973
    • journal article
    • Vol. 15  (2) , 153-6
Abstract
A review of the incidence of autoantibodies to normal tissue constituents in 250 patients with malignant disease has shown positive tests in 15% compared with 24% in patients with general non-neoplastic disorders and 8% in normal blood donors. In patients with lymphoma or leukaemia, the incidence of anti-smooth muscle antibodies was 15% compared with 4% in the control population; there was no increase in the incidence of anti-smooth muscle antibodies in patients with other malignant conditions. The incidence of anti-smooth muscle antibody in 4000 sera submitted for the investigation of possible autoimmune disorders is also reviewed.