IATROGENIC ULCERS
- 16 November 1964
- journal article
- editorial
- Published by American Medical Association (AMA) in JAMA
- Vol. 190 (7) , 681
- https://doi.org/10.1001/jama.1964.03070200117026
Abstract
Small-bowel ulceration distal to the duodenum is infrequently seen in practice. Consequently, when Baker and his co-workers in Minneapolis observed 12 patients with nonspecific ulcerations over a period of a little more than a year, they sought a common etiologic factor (this issue, p 586). At the time of their acute abdominal disease, 11 of these 12 patients were receiving enteric-coated medication which included a thiazide and potassium chloride as constituents. Several patients in the group had been treated for small-bowel obstruction previously; in 11 the presenting clinical picture in the present illness was small-bowel obstruction; all 12 had cardiovascular disease to some degree. The duration of drug therapy varied from eight days to 33 months; in some cases the apparent chronicity of the ulceration or stenosis did not correlate well with the duration of therapy. Although a relationship between ulceration and potassium chloride therapy is speculative, the authors feltKeywords
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