Temperature regulation of the cryptococcal phenoloxidase
- 1 January 1991
- journal article
- Published by Oxford University Press (OUP) in Medical Mycology
- Vol. 29 (2) , 121-124
- https://doi.org/10.1080/02681219180000201
Abstract
Melanin formation at 37 degrees C has been proposed as a virulence factor in Cryptococcus neoformans. However, whereas catecholamine uptake is maintained at this temperature, phenoloxidase, which catalyses the oxidation of catecholamine to melanin, is severely decreased in most wild type strains cultivated at 37 degrees C.Keywords
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