Enzymatic activity and filament assembly of Acanthamoeba myosin II are regulated by adjacent domains at the end of the tail
Open Access
- 18 July 1988
- journal article
- Published by Wiley in FEBS Letters
- Vol. 234 (2) , 435-438
- https://doi.org/10.1016/0014-5793(88)80132-7
Abstract
Polyclonal antibodies raised against a synthetic peptide consisting of the last 19 amino acids at the end of the coiled‐coil region of the heavy chains inhibited the actin‐activated Mg2+‐ATPase activity of myosin II and its ability to form filaments. Antibodies against a synthetic peptide corresponding to the 21 adjacent amino acids at the beginning of the non‐helical tailpiece, which include the three regulatory phosphorylatable serines, had no effect on either activity.Keywords
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