Abstract
Noon and Freeman, in 1911, published from Wright's laboratory in London the first reports of the successful treatment of hay-fever by active immunization.1In this country, Koessler,2in 1910, and Clowes3in 1913, first attempted the preventive treatment of the American or autumnal form of hay-fever. Thirteen years have scarcely elapsed since the first hope for relief has been given to the vast army of hay-fever patients. In fact, so recent is the innovation that not all the limitations or imperfections have been brought to light. Accordingly, some members of the profession have fallen victims to skepticism, whereas the sufferers from hay-fever have fallen prey to the numerous "cures" which are heralded in the lay press and journals. It is my purpose to record the results of an inquiry into the present status of the preventive treatment of seasonal hay-fever, and to disclose the possible causes of