Crystallographic and Spectroscopic Characterization of a Nonheme Fe(IV)=O Complex
Top Cited Papers
- 14 February 2003
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 299 (5609) , 1037-1039
- https://doi.org/10.1126/science.299.5609.1037
Abstract
Following the heme paradigm, it is often proposed that dioxygen activation by nonheme monoiron enzymes involves an iron(IV)=oxo intermediate that is responsible for the substrate oxidation step. Such a transient species has now been obtained from a synthetic complex with a nonheme macrocyclic ligand and characterized spectroscopically. Its high-resolution crystal structure reveals an iron-oxygen bond length of 1.646(3) angstroms, demonstrating that a terminal iron(IV)=oxo unit can exist in a nonporphyrin ligand environment and lending credence to proposed mechanisms of nonheme iron catalysis.Keywords
This publication has 33 references indexed in Scilit:
- “Intermolecular” Trapping of a Nonheme Fe(IV)O IntermediateInorganic Chemistry, 2001
- The Flexible Fe2(μ-O)2 Diamond Core: A Terminal Iron(IV)−Oxo Species Generated from the Oxidation of a Bis(μ-oxo)diiron(III) ComplexJournal of the American Chemical Society, 2000
- The Catalytic Pathway of Cytochrome P450cam at Atomic ResolutionScience, 2000
- Generation of oxoiron(IV) tetramesitylporphyrin π-cation radical complexes by m-CPBA oxidation of ferric tetramesitylporphyrin derivatives in butyronitrile at −78 °C. Evidence for the formation of six-coordinate oxoiron(IV) tetramesitylporphyrin π-cation radical complexes FeIV=O(tmp)X (X=Cl−, Br−), by Mössbauer and X-ray absorption spectroscopyJournal of Inorganic Biochemistry, 2000
- Mechanism of the Methane → Methanol Conversion Reaction Catalyzed by Methane Monooxygenase: A Density Functional StudyJournal of the American Chemical Society, 1999
- Evidence for a Nonheme Fe(IV)O Species in the Intramolecular Hydroxylation of a Phenyl MoietyJournal of the American Chemical Society, 1999
- Heme-Containing OxygenasesChemical Reviews, 1996
- High-valent transition metal chemistry. Moessbauer and EPR studies of high-spin (S = 2) iron(IV) and intermediate-spin (S = 3/2) iron(III) complexes with a macrocyclic tetraamido-N ligandJournal of the American Chemical Society, 1993
- Cytochrome c peroxidase compound ES is identical with horseradish peroxidase compound I in iron-ligand distancesBiochemistry, 1986
- Formation of an iron(IV)-oxo "picket-fence" porphyrin derivative via reduction of the ferrous dioxygen adduct and reaction with carbon dioxideJournal of the American Chemical Society, 1985