Fibrous histiocaytomas of the oral and maxillofacial regions

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Abstract
Fibrous histiocytomas of the oral and maxillofacial regions are rare. A sample of 63 cases from the literature together with 7 personally observed cases were analyzed. Age, sex, site, size, clinical behavior, treatment and survival were evaluated and related to a histological classification based on that of Rosai (1981). Lesions were assessed for histological criteria which would place them in 1 of 2 groups: fibrous histiocytoma (FH) or pleomorphic fibrous histiocytoma (PFH). Within these 2 histological groups the cases were subdivided into clinically benign, aggressive or malignant lesions. Thirty-nine cases (56.0%) were classified as FH and 31 cases (44.0%) as PFH. The mean age of male patients with PFH was significantly higher than female patients with FH (t = 3.05; d.f. 37; P < 0.0025). Lesions in the PFH group involved bone more frequently than those in the FH group (Yate''s Chi2 = 16.66; d.f. 1; P < 0.00025). Lesions involving bone for both histological groups were more likely to be aggressive or malignant than soft-tissue lesions (Yate''s Chi2 = 29.9; d.f. 1; P < 0.00025). Soft-tissue lesions were usually < 5 cm in greatest diameter. Radiographic features of malignancy for lesions with bone involvement is of prognostic importance regardless of the histological appearance of the lesion. The majority of the lesions under study were from the deep tissues of the oral and maxillofacial regions.

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