Genetic variations and treatments that affect the lifespan of the NPC1 mouse
Open Access
- 1 March 2008
- journal article
- Published by Elsevier in Journal of Lipid Research
- Vol. 49 (3) , 663-669
- https://doi.org/10.1194/jlr.m700525-jlr200
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- Liver X Receptor Activation Enhances Cholesterol Loss from the Brain, Decreases Neuroinflammation, and Increases Survival of the NPC1 MouseJournal of Neuroscience, 2007
- Receptor-mediated and bulk-phase endocytosis cause macrophage and cholesterol accumulation in Niemann-Pick C diseaseJournal of Lipid Research, 2007
- Lysosomal unesterified cholesterol content correlates with liver cell death in murine Niemann-Pick type C diseaseJournal of Lipid Research, 2007
- Cholesterol substrate pools and steroid hormone levels are normal in the face of mutational inactivation of NPC1 proteinJournal of Lipid Research, 2006
- Cholesterol Accumulation and Liver Cell Death in Mice With Niemann-Pick Type C Disease *Hepatology, 2005
- Model Systems, Lipid Rafts, and Cell MembranesAnnual Review of Biophysics, 2004
- Regulation of Cholesterol Homeostasis by the Liver X Receptors in the Central Nervous SystemMolecular Endocrinology, 2002
- Functional Loss of ABCA1 in Mice Causes Severe Placental Malformation, Aberrant Lipid Distribution, and Kidney Glomerulonephritis As Well As High-Density Lipoprotein Cholesterol DeficiencyThe American Journal of Pathology, 2000
- Regulation of Absorption and ABC1-Mediated Efflux of Cholesterol by RXR HeterodimersScience, 2000
- Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.Journal of Clinical Investigation, 1993