p23, a novel mammalian nucleic acid‐binding protein with homology to the yeast ribosomal protein YL43

Abstract
When separating perchloric acid‐soluble proteins from cell cultures and tissues by chromatography on single stranded DNA agarose columns, a novel mammalian protein with extreme affinity for DNA was isolated. Cellular localization, amino acid composition and the N‐terminal sequence suggest that the protein is a ribosomal protein with extensive sequence homology to the ribosomal protein, YL43, from Saccharomyces cerevisiae.