COMPARATIVE HAEMODYNAMIC EFFECTS OF CLONIDINE ADMINISTERED INTRAMUSCULARLY OR INTRAVENOUSLY TO ANAESTHETIZED RATS
- 1 April 1978
- journal article
- research article
- Published by Wiley in Clinical and Experimental Pharmacology and Physiology
- Vol. 5 (2) , 191-193
- https://doi.org/10.1111/j.1440-1681.1978.tb00670.x
Abstract
1. The acute haemodynamic effects of clonidine, 0.001-1.0 mg/kg, administered intramuscularly or intravenously, were studied in anaesthetized rats. 2. The direct pressor potency of clonidine was 100-fold greater following intravenous administration than after intramuscular injection, but hypotensive efficacy was equal by either route.Keywords
This publication has 2 references indexed in Scilit:
- INTERACTIONS BETWEEN PRAZOSIN, CLONIDINE AND DIRECT VASODILATORS IN THE ANAESTHETIZED RATClinical and Experimental Pharmacology and Physiology, 1978
- The Use of Clonidine by Intramuscular Injection in the Treatment of Hypertension*Australian and New Zealand Journal of Medicine, 1977