Infertility in Mice Exposed in utero to Benzo(a)pyrene1
- 1 February 1981
- journal article
- research article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 24 (1) , 183-191
- https://doi.org/10.1095/biolreprod24.1.183
Abstract
The carcinogenic polycyclic hydrocarbon benzo(a)pyrene(BP) is a ubiquitous urban pollutant and is a component of cigarette smoke. Studies reported here were designed to investigate the effect of daily oral doses of 0, 10, 40, and 160 mg BP/kg maternal BW on Days 7-16 of gestation on pregnancy maintenance, and on fetal development and survival of CD-1 mice. Postnatal development and reproductive function also were investigated in F1 male and female mice exposed to BP in utero.Keywords
This publication has 15 references indexed in Scilit:
- Chromosome aberrations in oocytes of NMRI mice and bone marrow cells of Chinese hamsters induced with 3,4-benzpyreneMutation Research/Environmental Mutagenesis and Related Subjects, 1976
- Chemically induced presumed somatic mutations in the mouseMutation Research/Environmental Mutagenesis and Related Subjects, 1976
- Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cells.Proceedings of the National Academy of Sciences, 1976
- SOME RESULTS AND PROSPECTS OF TRANSPLACENTAL CARCINOGENESIS STUDIES1976
- CARCINOGENESIS IN AKR MICE INJECTED AT BIRTH WITH BENZO(A) PYRENE AND DIMETHYLNITROSAMINE1967
- Airborne Carcinogens and Allied CompoundsArchives of environmental health, 1967
- Radiation Sensitivity of the Mouse Ovary: Fertility and Oocyte SurvivalFertility and Sterility, 1964
- The Effect of Phenanthrene on Tumour Induction by 3,4-Benzopyrene Administered to Newly Born MiceBritish Journal of Cancer, 1963
- Induction of Carcinoma and Papilloma of the Tracheobronchial Mucosa of the Syrian Hamster by Intratracheal Instillation of Benzo[α]-pyreneJNCI Journal of the National Cancer Institute, 1962
- STUDIES OF SKIN CARCINOGENESIS IN THE SYRIAN GOLDEN HAMSTER1960