Health-Related Quality of Life in Inflammatory Bowel Disease
- 1 October 1996
- journal article
- Published by Springer Nature in PharmacoEconomics
- Vol. 10 (4) , 327-335
- https://doi.org/10.2165/00019053-199610040-00003
Abstract
Inflammatory bowel disease (IBD) is characterised by a chronic, but frequently remitting, clinical course involving significant morbidity. As medical and surgical advances have occurred, focus has shifted from merely reducing mortality to efforts on decreasing morbidity and improving health status. With this paradigm shift has come the need for qualitative and quantitative assessment of outcomes important to the individual patient. Existing disease activity measures fall short in this area. Health-related quality of life encompasses the areas of physical function, somatic sensation, psychological state and social interactions that are affected by one’s health status. Instruments have recently been developed for both generic and disease-specific health states, such as IBD. These psychometric measures have proven to be useful tools for patient assessment. Both medical and surgical trials have incorporated these measures as salient outcomes. An additional outcome that has come under closer scrutiny is the cost of medical interventions. The literature on the cost of IBO is sparse but is likely to increase logarithmically in the future. Quality of life and cost issues are becoming central to the study of not just IBO but all of medicine.Keywords
This publication has 33 references indexed in Scilit:
- Review article: assessment of drug therapy in inflammatory bowel diseaseAlimentary Pharmacology & Therapeutics, 2007
- Quality-of-life results of double-blind, placebo-controlled trial of mesalamine in patients with Crohn's diseaseDigestive Diseases and Sciences, 1995
- Ulcerative Colitis and Crohnʼs Disease Health Status Scales for Research and Clinical PracticeJournal of Clinical Gastroenterology, 1992
- Quality of Life Instruments in the Evaluation of New DrugsPharmacoEconomics, 1992
- Quality of Life in Inflammatory Bowel DiseaseJournal of Clinical Gastroenterology, 1992
- Health status and health care use in persons with inflammatory bowel diseaseDigestive Diseases and Sciences, 1991
- Appraisal, coping, health status, and psychological symptoms.Journal of Personality and Social Psychology, 1986
- A methodological framework for assessing health indicesJournal of Chronic Diseases, 1985
- Correlations between defined sigmoidoscopic appearances and other measures of disease activity in ulcerative colitisDigestive Diseases and Sciences, 1982
- A SIMPLE INDEX OF CROHN'S-DISEASE ACTIVITYThe Lancet, 1980