Evidence in man for different specialized intestinal transport mechanisms for riboflavin and thiamin
Open Access
- 1 April 1971
- journal article
- clinical trial
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 24 (4) , 401-404
- https://doi.org/10.1093/ajcn/24.4.401
Abstract
Large oral doses of riboflavin and thiamin do not affect the absorption of one another in man. The absorption of a large dose of riboflavin is much greater when given after breakfast than on an empty stomach, whereas the extent of absorption of thiamin is not affected significantly by food. Although riboflavin and thiamin are absorbed by saturable intestinal transport mechanisms and are both phosphorylated during absorption, the results of this investigation suggest that the two vitamins do not share a common specialized absorption pathway.Keywords
This publication has 6 references indexed in Scilit:
- Phosphorylation and uphill intestinal transport of thiamine, in vitroCellular and Molecular Life Sciences, 1967
- Absorption, Metabolism, and Excretion of Riboflavin-5′-phosphate in ManJournal of Pharmaceutical Sciences, 1967
- Factors Affecting the Absorption of Riboflavin in ManJournal of Pharmaceutical Sciences, 1966
- Transport of thiamine by the small intestine in vitroCellular and Molecular Life Sciences, 1965
- Intestinal Absorption of Riboflavin by ManActa Pharmacologica et Toxicologica, 1965
- THE DETERMINATION OF THIAMINE IN URINE BY MEANS OF THE THIOCHROME TECHNIQUEPublished by Elsevier ,1945