Fluorescent Antibody Staining of Street and Fixed Rabies Virus Antigens

Abstract
Methods of fixing and staining of rabies-infected mouse brain smears with fluorescent antibody are described. Evidence is presented that Negri bodies are of viral origin. The possible usefulness of this method for the diagnosis of rabies in Negri negative animals and for serological determinations following immunization against rabies is indicated. Preliminary studies indicate that this technique may be useful in the detection of virus in salivary glands.

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