Effect of antibodies to human seminal plasma inhibin on spermatogenesis and sperm agglutination in adult male rats

1 March 1990

journal article
research article
Published by Wiley in Molecular Reproduction and Development

Vol. 25 (3) , 227-236
https://doi.org/10.1002/mrd.1080250304

Abstract

In vitro incubation of rat epididymal sperm with antiserum to human seminal plasma inhibin (As hSPl) caused agglutination of the sperm. In vivo administration of As hSPl to adult male rats resulted in a significant decrease in testicular as well as epididymal sperm counts. Furthermore, the majority (almost 90%) of the epididymal sperm were agglutinated. When these animals were mated with normal cycling females, significant reduction in fertility was observed.

Keywords

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